TMC1 [YOR052C]
Trivalent metalloid-sensitive Cuz1-related protein 1; AN1-type zinc finger protein, effector of proteotoxic stress response; stress-inducible transcriptional target of Rpn4p; induced by nitrogen limitation, weak acid, misfolded proteins; short-lived protein, degraded by proteasome; may protect cells from trivalent metalloid induced proteotoxicity; contains PACE promoter element; ortholog of human AIRAP, which stimulates proteasome activity in response to arsenic; protein abundance increases under DNA replication stress
Synonyms: TMC1, TMC1p, YOR052C, Q08422, YOR052Cp ...