Cyclebase 3.0

Cell-cycle regulation database

PAP2 [YOL115W]

Topoisomerase 1-related protein TRF4; Non-canonical poly(A) polymerase; involved in nuclear RNA degradation as a component of TRAMP; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; required for mRNA surveillance and maintenance of genome integrity, serving as a link between RNA and DNA metabolism; overlapping but non-redundant functions with Trf5p; relocalizes to cytosol in response to hypoxia

Synonyms:  PAP2,  PAP2p,  P53632,  HRC584,  O0716 ...

Linkouts:  STRING  UniProt