MSB4 [YOL112W]
Multicopy suppressor of bud emergence 4; GTPase-activating protein of the Ras superfamily; acts primarily on Sec4p, localizes to the bud site and bud tip; msb3 msb4 double mutation causes defects in secretion and actin organization; similar to the TBC-domain Tre2 oncogene; MSB4 has a paralog, MSB3, that arose from the whole genome duplication; human homolog USP6NL can complement yeast msb3 msb4 double null mutant
Synonyms: MSB4, MSB4p, Q12317, HRC492, Q12317p ...