Cyclebase 3.0

Cell-cycle regulation database

TRM10 [YOL093W]

tRNA methyltransferase; methylates the N-1 position of guanine at position 9 in tRNAs; protein abundance increases in response to DNA replication stress; member of the SPOUT (SpoU-TrmD) methyltransferase family; human ortholog TRMT10A plays a role in the pathogenesis of microcephaly and early onset diabetes; an 18-mer originates from the TRM10 locus; genetic analysis shows the 18-mer is the translation regulator; Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family.

Synonyms:  TRM10,  TRM10p,  Q12400,  O0926,  Q12400p ...

Linkouts:  STRING  UniProt