Cyclebase 3.0

Cell-cycle regulation database

MHF1 [YOL086W-A]

MPH1-associated histone-fold protein 1; Component of the heterotetrameric MHF histone-fold complex; in humans the MHF complex interacts with both DNA and Mph1p ortholog FANCM, a Fanconi anemia complementation group protein, to stabilize and remodel blocked replication forks and repair damaged DNA; mhf1 srs2 double mutants are MMS hypersensitive; ortholog of human centromere constitutive-associated network (CCAN) subunit CENP-S, also known as MHF1

Synonyms:  MHF1,  MHF1p,  YOL086W-A,  Q3E835,  YOL086W-Ap ...

Linkouts:  STRING  UniProt