APM4 [YOL062C]
Mu2-like subunit of the clathrin associated protein complex (AP-2); involved in vesicle transport; Cargo-binding mu subunit of AP-2; AP-2 is a heterotetrameric endocytic cargo-binding adaptor that facilitates uptake of membrane proteins during clathrin-mediated endocytosis; Apm4p is required for AP-2 function and localization, and binds cell wall stress receptor Mid2p; AP-2 is required for cell polarity responses to pheromone, nutritional status and cell wall damage in S. cerevisiae, and for hyphal growth in C. albicans; AP-2 complex is conserved in mammals; Belongs to the adaptor complexes medium subunit family.
Synonyms: APM4, APM4p, Q99186, AMP1, O1210 ...