Cyclebase 3.0

Cell-cycle regulation database

SSK2 [YNR031C]

MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication

Synonyms:  SSK2,  SSK2p,  P53599,  N3276,  P53599p ...

Linkouts:  STRING  UniProt