Cyclebase 3.0

Cell-cycle regulation database

PUS4 [YNL292W]

tRNA pseudouridine(55) synthase; Pseudouridine synthase; catalyzes only the formation of pseudouridine-55 (Psi55), a highly conserved tRNA modification, in mitochondrial and cytoplasmic tRNAs; also responsible for pseudouracil modification of some mRNAs; PUS4 overexpression leads to translational derepression of GCN4 (Gcd- phenotype)

Synonyms:  PUS4,  PUS4p,  P48567,  N0480,  P48567p ...

Linkouts:  STRING  UniProt