Cyclebase 3.0

Cell-cycle regulation database

HCH1 [YNL281W]

High-copy Hsp90 suppressor protein 1; Heat shock protein regulator; binds to Hsp90p and may stimulate ATPase activity; originally identified as a high-copy number suppressor of a HSP90 loss-of-function mutation; role in regulating Hsp90 inhibitor drug sensitivity; GFP-fusion protein localizes to the cytoplasm and nucleus; protein abundance increases in response to DNA replication stress; Belongs to the AHA1 family.

Synonyms:  HCH1,  HCH1p,  P53834,  N0589,  P53834p ...

Linkouts:  STRING  UniProt