Cyclebase 3.0

Cell-cycle regulation database

WHI3 [YNL197C]

RNA binding protein that sequesters CLN3 mRNA in cytoplasmic foci; regulates genes involved in the cell cycle, sister chromatid cohesion, and stress response; acts as a cytoplasmic retention factor for Cdc28p and associated cyclins; regulates cell fate and dose-dependently regulates the critical cell size required for passage through Start; Tpk1p (PKA) mediated phosphorylation (S568) inhibits Whi3p function, decreasing its interaction with CLN3 mRNA; regulates ploidy

Synonyms:  WHI3,  WHI3p,  P34761,  N1382,  P34761p ...

Linkouts:  STRING  UniProt