Cyclebase 3.0

Cell-cycle regulation database

SRP1 [YNL189W]

Serine-rich RNA polymerase I suppressor protein; Karyopherin alpha homolog; forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; involved in cotranslational protein degradation; binds ribosome-bound nascent polypeptides; Srp1p and Sts1p couple proteasomes to nascent polypeptides emerging from the ribosome for cotranslational degradation

Synonyms:  SRP1,  SRP1p,  Q02821,  KAP60,  N1606 ...

Linkouts:  STRING  UniProt