Cyclebase 3.0

Cell-cycle regulation database

UBP10 [YNL186W]

Disrupter of telomere silencing protein 4; Ubiquitin-specific protease, deubiquitinates Ub-protein moieties; interacts with proteins that function in rRNA production and ribosome biogenesis via its intrinsically disordered regions; stabilizes Rpa190p by deubiquitination; controls PCNA deubiquitylation; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p, possibly other transporters; localized to the nucleolus; null mutant phenotypes are functionally complemented by human USP36

Synonyms:  UBP10,  UBP10p,  P53874,  DOT4,  N1619 ...

Linkouts:  STRING  UniProt