Cyclebase 3.0

Cell-cycle regulation database

SRV2 [YNL138W]

CAP (cyclase-associated protein); N-terminus binds adenylate cyclase and facilitates activation by RAS; N-terminus forms novel hexameric star-shaped shuriken structures that directly catalyze cofilin-mediated severing of actin filaments; C-terminus binds and recycles cofilin bound, ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis; N- and C-termini can function as physically separate proteins; mCAP1 is the mouse homolog

Synonyms:  SRV2p,  P17555,  CAP1,  N1210,  N1838 ...

Linkouts:  STRING  UniProt