Cyclebase 3.0

Cell-cycle regulation database

MRE11 [YMR224C]

Double-strand break repair protein MRE11; Nuclease subunit of the MRX complex with Rad50p and Xrs2p; complex functions in repair of DNA double-strand breaks and in telomere stability; Mre11p associates with Ser/Thr-rich ORFs in premeiotic phase; nuclease activity required for MRX function; widely conserved; forms nuclear foci upon DNA replication stress; Belongs to the MRE11/RAD32 family.

Synonyms:  MRE11p,  P32829,  P32829p,  YM9959.06C,  YMR224C ...

Linkouts:  STRING  UniProt