Cyclebase 3.0

Cell-cycle regulation database

MLH1 [YMR167W]

Post meiotic segregation protein 2; Protein required for mismatch repair in mitosis and meiosis; also required for crossing over during meiosis; forms a complex with Pms1p and Msh2p-Msh3p during mismatch repair; human homolog is associated with hereditary non-polyposis colon cancer; Belongs to the DNA mismatch repair MutL/HexB family.

Synonyms:  MLH1,  MLH1p,  P38920,  P38920p,  PMS2 ...

Linkouts:  STRING  UniProt