Cyclebase 3.0

Cell-cycle regulation database

YKU80 [YMR106C]

ATP-dependent DNA helicase II subunit Ku80; Subunit of telomeric Ku complex (Yku70p-Yku80p); involved in telomere length maintenance, structure and telomere position effect; required for localization of telomerase ribonucleoprotein via interaction with TLC1 guide RNA; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair; colocalizes with quiescent cell telomere hyperclusters; Belongs to the ku80 family.

Synonyms:  YKU80,  YKU80p,  Q04437,  HDF2,  Q04437p ...

Linkouts:  STRING  UniProt