Cyclebase 3.0

Cell-cycle regulation database

AIP1 [YMR092C]

Actin-interacting protein 1; Actin cortical patch component; interacts with the actin depolymerizing factor cofilin; inhibits elongation of aged ADP-actin filaments decorated with cofilin to maintain a high level of assembly-competent actin species; required to restrict cofilin localization to cortical patches; putative regulator of cytokinesis; contains WD repeats; protein increases in abundance and relocalizes from cytoplasm to plasma membrane upon DNA replication stress

Synonyms:  AIP1,  AIP1p,  P46680,  P46680p,  YM9582.17C ...

Linkouts:  STRING  UniProt