Cyclebase 3.0

Cell-cycle regulation database

UBX4 [YMR067C]

UBX domain-containing protein that interacts with Cdc48p; involved in degradation of polyubiquitinated proteins via the ERAD (ER-associated degradation) pathway; modulates the Cdc48p-Nplp-Ufd1p AAA ATPase complex during its role in delivery of misfolded proteins to the proteasome; protein abundance increases in response to DNA replication stress

Synonyms:  UBX4,  UBX4p,  P54730,  P54730p,  YM9916.06C ...

Linkouts:  STRING  UniProt