Cyclebase 3.0

Cell-cycle regulation database

HOF1 [YMR032W]

Homolog of CDC15 protein 1; Protein that regulates actin cytoskeleton organization; required for cytokinesis, actin cable organization, and secretory vesicle trafficking; localized to bud neck; phosphorylated by Dbf2p; regulates actomyosin ring dynamics and septin localization; contains an SH3 domain; N terminus controls cell size and levels of actin cables, while C terminus controls actin cable organization via direct regulation of the formin Bnr1p

Synonyms:  HOF1,  HOF1p,  Q05080,  CYK2,  Q05080p ...

Linkouts:  STRING  UniProt