Cyclebase 3.0

Cell-cycle regulation database

HUG1 [YML058W-A]

MEC1-mediated checkpoint protein HUG1; Ribonucleotide reductase inhibitor; intrinsically disordered protein that binds to and inhibits Rnr2p; involved in the Mec1p-mediated checkpoint pathway; transcription is induced by genotoxic stress and by activation of the Rad53p pathway; protein abundance increases in response to DNA replication stress

Synonyms:  HUG1,  HUG1p,  Q6Q5K6,  Q6Q5K6p,  YML058W-A ...

Linkouts:  STRING  UniProt