Cyclebase 3.0

Cell-cycle regulation database

SPT5 [YML010W]

Spt4p/5p (DSIF) transcription elongation factor complex subunit; the Spt4/5 complex binds to ssRNA in a sequence-specific manner, and in concert with RNAP I and II has multiple roles regulating transcriptional elongation, RNA processing, quality control, and transcription-coupled repair; interacts with DNA upstream of RNAPII and the non-template strand of the transcription bubble; Spt5p is the only transcription elongation factor conserved in all domains of life

Synonyms:  SPT5,  SPT5p,  P27692,  P27692p,  YM9571.08 ...

Linkouts:  STRING  UniProt