Cyclebase 3.0

Cell-cycle regulation database

ORM2 [YLR350W]

Protein that mediates sphingolipid homeostasis; evolutionarily conserved, required for resistance to agents that induce unfolded protein response; Orm1p and Orm2p together control membrane biogenesis by coordinating lipid homeostasis with protein quality control; protein abundance increases in response to DNA replication stress; ORM2 has a paralog, ORM1, that arose from the whole genome duplication

Synonyms:  ORM2,  ORM2p,  Q06144,  Q06144p,  YLR350W ...

Linkouts:  STRING  UniProt