Cyclebase 3.0

Cell-cycle regulation database

VPS34 [YLR240W]

Vacuolar protein sorting-associated protein 34; Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; activated by the GTP-bound form of Gpa1p; a fraction is localized, with Vps15p, to nuclear pores at nucleus-vacuole junctions and may facilitate transcription elongation for genes positioned at the nuclear periphery; Belongs to the PI3/PI4-kinase family.

Synonyms:  VPS34,  VPS34p,  P22543,  END12,  L9672.10 ...

Linkouts:  STRING  UniProt