Cyclebase 3.0

Cell-cycle regulation database

TOP3 [YLR234W]

DNA Topoisomerase III; conserved protein that functions in a complex with Sgs1p and Rmi1p to relax single-stranded negatively-supercoiled DNA preferentially; DNA catenation/decatenation activity is stimulated by RPA and Sgs1p-Top3p-Rmi1p; involved in telomere stability and regulation of mitotic recombination

Synonyms:  TOP3,  TOP3p,  P13099,  EDR1,  L8083.3 ...

Linkouts:  STRING  UniProt