Cyclebase 3.0

Cell-cycle regulation database

TOS4 [YLR183C]

Target of SBF protein 4; Putative transcription factor, contains Forkhead Associated domain; binds chromatin; involved in expression homeostasis, buffering of mRNA synthesis rate against gene dosage changes during S phase; target of SBF transcription factor; expression is periodic and peaks in G1; involved in DNA replication checkpoint response; interacts with Rpd3 and Set3 histone deacetylase complexes; APCC(Cdh1) substrate; relative distribution to nucleus increases upon DNA replication stress

Synonyms:  TOS4,  TOS4p,  Q06266,  L94705.22,  Q06266p ...

Linkouts:  STRING  UniProt