Cyclebase 3.0

Cell-cycle regulation database

SLX4 [YLR135W]

Synthetic lethal of unknown function protein 4; Endonuclease involved in processing DNA; acts during recombination, repair; promotes template switching during break-induced replication (BIR), causing non-reciprocal translocations (NRTs); cleaves branched structures in complex with Slx1p; involved in interstrand cross-link repair, Rad1p/Rad10p-dependent removal of 3'-nonhomologous tails during DSBR via single-strand annealing; relative distribution to nuclear foci increases upon DNA replication stress; FANCP-related factor; Belongs to the SLX4 family.

Synonyms:  SLX4,  SLX4p,  Q12098,  L3140,  Q12098p ...

Linkouts:  STRING  UniProt