Cyclebase 3.0

Cell-cycle regulation database

ALT1 [YLR089C]

Probable alanine aminotransferase, mitochondrial; Alanine transaminase (glutamic pyruvic transaminase); involved in alanine biosynthesis and catabolism; TOR1-independent role in determining chronological lifespan; expression is induced in the presence of alanine; repression is mediated by Nrg1p; ALT1 has a paralog, ALT2, that arose from the whole genome duplication; Alt2p is catalytically inactive; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.

Synonyms:  ALT1,  ALT1p,  P52893,  L9449.15,  P52893p ...

Linkouts:  STRING  UniProt