PDC1 [YLR044C]
Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; Major of three pyruvate decarboxylase isozymes; key enzyme in alcoholic fermentation; decarboxylates pyruvate to acetaldehyde; involved in amino acid catabolism; subject to glucose-, ethanol-, and autoregulation; activated by phosphorylation in response to glucose levels; N-terminally propionylated in vivo; Belongs to the TPP enzyme family.
Synonyms: PDC1, PDC1p, P06169, L2104, P06169p ...