DPS1 [YLL018C]
Aspartate--tRNA ligase, cytoplasmic; Aspartyl-tRNA synthetase, primarily cytoplasmic; homodimeric enzyme that catalyzes the specific aspartylation of tRNA(Asp); class II aminoacyl tRNA synthetase; binding to its own mRNA may confer autoregulation; shares five highly conserved amino acids with human that when mutated cause leukoencephalopathy characterized by hypomyelination with brain stem and spinal cord involvement and leg spasticity (HBSL); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
Synonyms: DPS1, DPS1p, P04802, APS, APS1 ...