Cyclebase 3.0

Cell-cycle regulation database

RTT109 [YLL002W]

Regulator of Ty1 transposition protein 109; Histone acetyltransferase; critical for cell survival in presence of DNA damage during S phase, required for recovery after DSB repair; acetylates H3K56, H3K9; H3K56 acetylation activity required for expression homeostasis, buffering of mRNA synthesis rate against changes in gene dosage during S phase; involved in non-homologous end joining and regulation of Ty1 transposition; prevents hyper-amplification of rDNA; interacts physically with Vps75p

Synonyms:  RTT109,  RTT109p,  Q07794,  KIM2,  L1377 ...

Linkouts:  STRING  UniProt