Cyclebase 3.0

Cell-cycle regulation database

LAS1 [YKR063C]

Protein LAS1; Endonuclease involved in pre-rRNA processing at both ends of ITS2; functions with Grc3p in a conserved mechanism to modulate rRNA processing and ribosome biogenesis; may coordinate the action of the Rat1p-Rai1p exoRNAse; required for the G1/S cell cycle transition; human ortholog is Las1L; mutants require the SSD1-v allele for viability

Synonyms:  LAS1p,  P36146,  P36146p,  YKR063C,  853937 ...

Linkouts:  STRING  UniProt