Cyclebase 3.0

Cell-cycle regulation database

TIF1 [YKR059W]

Stimulator factor I 37 kDa component; Translation initiation factor eIF4A; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G; protein abundance increases in response to DNA replication stress; TIF1 has a paralog, TIF2, that arose from the whole genome duplication

Synonyms:  TIF1,  TIF1p,  TIF2,  P10081,  TIF2p ...

Linkouts:  STRING  UniProt