Cyclebase 3.0

Cell-cycle regulation database

SPO14 [YKR031C]

Meiosis-specific sporulation-specific protein 14; Phospholipase D; catalyzes the hydrolysis of phosphatidylcholine, producing choline and phosphatidic acid; involved in Sec14p-independent secretion; required for meiosis and spore formation; differently regulated in secretion and meiosis; participates in transcription initiation and/or early elongation of specific genes; interacts with "foot domain" of RNA polymerase II; deletion results in abnormal CTD-Ser5 phosphorylation of RNA polymerase II at specific promoter regions

Synonyms:  SPO14,  SPO14p,  P36126,  P36126p,  PLD1 ...

Linkouts:  STRING  UniProt