Cyclebase 3.0

Cell-cycle regulation database

TOF2 [YKR010C]

Topoisomerase 1-associated factor 2; Protein required for rDNA silencing and mitotic rDNA condensation; stimulates Cdc14p phosphatase activity and biphasic release to promote rDNA repeat segregation; required for condensin recruitment to the replication fork barrier site; TOF2 has a paralog, NET1, that arose from the whole genome duplication; To yeast YJL076w.

Synonyms:  TOF2,  TOF2p,  Q02208,  Q02208p,  YK109 ...

Linkouts:  STRING  UniProt