COS5 [YJR161C]
Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins; Belongs to the DUP/COS family.
Synonyms: COS5, COS5p, P47187, J2410, P47187p ...