Cyclebase 3.0

Cell-cycle regulation database

MNS1 [YJR131W]

Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase; Alpha-1,2-mannosidase; involved in ER-associated protein degradation (ERAD); catalyzes the removal of one mannose residue from a glycosylated protein, converting the modification from Man9GlcNAc to Man8GlcNAc; catalyzes the last step in glycoprotein maturation in the ER and is critical for ER protein degradation; Belongs to the glycosyl hydrolase 47 family.

Synonyms:  MNS1,  MNS1p,  P32906,  J2110,  P32906p ...

Linkouts:  STRING  UniProt