ESS1 [YJR017C]
Peptidyl-prolyl cis-trans isomerase ESS1; Peptidylprolyl-cis/trans-isomerase (PPIase); specific for phosphorylated S/T residues N-terminal to proline; regulates phosphorylation of RNAPII large subunit (Rpo21p) C-terminal domain (CTD) at Ser7; associates with phospho-Ser5 form of RNAPII in vivo; present along entire coding length of genes; represses initiation of CUTs; required for efficient termination of mRNA transcription, trimethylation of histone H3; human ortholog PIN1 can complement yeast null and ts mutants; Belongs to the PpiC/parvulin rotamase family.
Synonyms: ESS1, ESS1p, P22696, J1452, P22696p ...