Cyclebase 3.0

Cell-cycle regulation database

TIF2 [YJL138C]

Translation initiation factor eIF4A; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G; protein abundance increases in response to DNA replication stress; TIF2 has a paralog, TIF1, that arose from the whole genome duplication

Synonyms:  TIF2,  TIF2p,  eIF4A,  L000002303,  NM_001181571 ...

Linkouts:  STRING