Cyclebase 3.0

Cell-cycle regulation database

EXO70 [YJL085W]

Subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis prior to SNARE-mediated fusion; PtdIns[4,5]P2-binding protein that localizes to exocytic sites in an actin-independent manner, targeting and anchoring the exocyst with Sec3p; involved in exocyst assembly; direct downstream effector of Rho3p and Cdc42p; relocalizes from bud neck to cytoplasm upon DNA replication stress

Synonyms:  EXO70,  EXO70p,  P19658,  J0932,  P19658p ...

Linkouts:  STRING  UniProt