Cyclebase 3.0

Cell-cycle regulation database

MAD2 [YJL030W]

Component of the spindle-assembly checkpoint complex; delays onset of anaphase in cells with defects in mitotic spindle assembly; forms a complex with Mad1p; regulates APC/C activity during prometaphase and metaphase of meiosis I; gene dosage imbalance between MAD1 and MAD2 leads to chromosome instability

Synonyms:  MAD2,  MAD2p,  P40958,  J1256,  P40958p ...

Linkouts:  STRING  UniProt