Cyclebase 3.0

Cell-cycle regulation database

MAD3 [YJL013C]

Subunit of spindle-assembly checkpoint complex; involved in delaying anaphase onset in cells with defects in mitotic spindle assembly; pseudosubstrate inhibitor of APC(Cdc20), the anaphase promoting complex involved in securin (Pds1p) turnover; MAD3 has a paralog, BUB1, that arose from the whole genome duplication

Synonyms:  MAD3,  MAD3p,  P47074,  J1341,  P47074p ...

Linkouts:  STRING  UniProt