Cyclebase 3.0

Cell-cycle regulation database

APQ12 [YIL040W]

Nuclear envelope/ER integral membrane protein; interacts and functions with Brr6p and Brl1p in lipid homeostasis; mutants are defective in nuclear pore complex biogenesis, nuclear envelope morphology, mRNA export from the nucleus and are sensitive to sterol biosynthesis inhibitors and membrane fluidizing agents; exhibits synthetic lethal genetic interactions with genes involved in lipid metabolism

Synonyms:  APQ12,  APQ12p,  P40532,  P40532p,  YIL040W ...

Linkouts:  STRING  UniProt