Cyclebase 3.0

Cell-cycle regulation database

ATG7 [YHR171W]

Ubiquitin-like modifier-activating enzyme ATG7; Autophagy-related protein and dual specificity member of the E1 family; mediates the attachment of Atg12p to Atg5p and Atg8p to phosphatidylethanolamine which are required steps in autophagosome formation; E1 enzymes are also known as ubiquitin-activating enzymes; involved in methionine restriction extension of chronological lifespan in an autophagy-dependent manner; Belongs to the ATG7 family.

Synonyms:  ATG7,  ATG7p,  P38862,  APG7,  CVT2 ...

Linkouts:  STRING  UniProt