Cyclebase 3.0

Cell-cycle regulation database

RTT107 [YHR154W]

Regulator of Ty1 transposition protein 107; Protein implicated in Mms22-dependent DNA repair during S phase; involved in recruiting the SMC5/6 complex to double-strand breaks; DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition; relative distribution to nuclear foci increases upon DNA replication stress

Synonyms:  RTT107,  RTT107p,  P38850,  ESC4,  P38850p ...

Linkouts:  STRING  UniProt