WSS1 [YHR134W]
DNA-dependent metalloprotease WSS1; SUMO-ligase and SUMO-targeted metalloprotease; involved in DNA repair; removes DNA-protein crosslinks at stalled replication forks during replication of damaged DNA; clears chromatin-bound sumoylated proteins; localizes to single spot on nuclear periphery of mother cells but not daughters; exhibits vacuolar localization upon genotoxic stress; activated by DNA binding; member of minigluzincins protease family with mammalian DVC1/Spartan; Belongs to the peptidase M3 family. WSS1-like metalloprotease (WLM) subfamily.
Synonyms: WSS1, WSS1p, P38838, P38838p, YHR134W ...