Cyclebase 3.0

Cell-cycle regulation database

SFB3 [YHR098C]

Lethal with SEC13 protein 1; Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat; COPII coat is required for cargo selection during vesicle formation in ER to Golgi transport; scaffolding function of Lst1p required to generate vesicles that can accommodate difficult cargo proteins that include large oligomeric assemblies and asymmetrically distributed membrane proteins; homologous to Sec24p and Sfb2p; Belongs to the SEC23/SEC24 family. SEC24 subfamily.

Synonyms:  SFB3,  SFB3p,  P38810,  LST1,  P38810p ...

Linkouts:  STRING  UniProt