Cyclebase 3.0

Cell-cycle regulation database

ERG11 [YHR007C]

Lanosterol 14-alpha-demethylase; catalyzes C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in ergosterol biosynthesis pathway; transcriptionally down-regulated when ergosterol is in excess; member of cytochrome P450 family; associated and coordinately regulated with the P450 reductase Ncp1p; human CYP51A1 functionally complements the lethality of the erg11 null mutation

Synonyms:  ERG11,  ERG11p,  P10614,  CYP51,  P10614p ...

Linkouts:  STRING  UniProt