Cyclebase 3.0

Cell-cycle regulation database

BUD32 [YGR262C]

Atypical serine/threonine protein kinase BUD32; Protein kinase; component of the EKC/KEOPS complex with Kae1p, Cgi121p, Pcc1p, and Gon7p; Pyrococcus Bud32 ortholog functions as a P-loop ATPase rather than a protein kinase in the context of the complex; EKC/KEOPS complex is required for t6A tRNA modification and telomeric TG1-3 recombination; may have role in transcription; mutation is functionally complemented by human TP53RK

Synonyms:  BUD32,  BUD32p,  P53323,  LDB14,  P53323p ...

Linkouts:  STRING  UniProt