Cyclebase 3.0

Cell-cycle regulation database

TRX2 [YGR209C]

Cytoplasmic thioredoxin isoenzyme; part of thioredoxin system which protects cells against oxidative and reductive stress; forms LMA1 complex with Pbi2p; acts as a cofactor for Tsa1p; required for ER-Golgi transport and vacuole inheritance; with Trx1p, facilitates mitochondrial import of small Tims Tim9p, Tim10p, Tim13p by maintaining them in reduced form; abundance increases under DNA replication stress; TRX2 has a paralog, TRX1, that arose from the whole genome duplication

Synonyms:  TRX2,  TRX2p,  P22803,  G7746,  P22803p ...

Linkouts:  STRING  UniProt