Cyclebase 3.0

Cell-cycle regulation database

SYF2 [YGR129W]

Synthetic lethal with CDC40 protein 2; Member of the NineTeen Complex (NTC); NTC contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; relocalizes to the cytosol in response to hypoxia; isy1 syf2 cells have defective spindles activiating cell cycle arrest

Synonyms:  SYF2,  SYF2p,  P53277,  NTC31,  P53277p ...

Linkouts:  STRING  UniProt